Lentiviral standards to determine the sensitivity of assays that quantify lentiviral vector copy numbers and genomic insertion sites in cells

With an increasing number of gene therapy clinical trials and drugs reaching the market, it becomes important to standardize the methods that evaluate the efficacy and safety of gene therapy. We herein report the generation of lentiviral standards which are stable, cloned human cells prepared from t...

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Detalles Bibliográficos
Autores principales: Corre, Guillaume, Seye, Ababacar, Frin, Sophie, Ferrand, Maxime, Winkler, Kathrin, Luc, Cyril, Dorange, Fabien, Rocca, Céline J., Galy, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482878/
https://www.ncbi.nlm.nih.gov/pubmed/35194185
http://dx.doi.org/10.1038/s41434-022-00315-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482878/
https://www.ncbi.nlm.nih.gov/pubmed/35194185
http://dx.doi.org/10.1038/s41434-022-00315-8

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