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Lentiviral standards to determine the sensitivity of assays that quantify lentiviral vector copy numbers and genomic insertion sites in cells
With an increasing number of gene therapy clinical trials and drugs reaching the market, it becomes important to standardize the methods that evaluate the efficacy and safety of gene therapy. We herein report the generation of lentiviral standards which are stable, cloned human cells prepared from t...
Autores principales: | Corre, Guillaume, Seye, Ababacar, Frin, Sophie, Ferrand, Maxime, Winkler, Kathrin, Luc, Cyril, Dorange, Fabien, Rocca, Céline J., Galy, Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482878/ https://www.ncbi.nlm.nih.gov/pubmed/35194185 http://dx.doi.org/10.1038/s41434-022-00315-8 |
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