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Advances in Antitumor Nano-Drug Delivery Systems of 10-Hydroxycamptothecin
10-Hydroxycamptothecin (HCPT) is a natural plant alkaloid from Camptotheca that shows potent antitumor activity by targeting intracellular topoisomerase I. However, factors such as instability of the lactone ring and insolubility in water have limited the clinical application of this drug. In recent...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482956/ https://www.ncbi.nlm.nih.gov/pubmed/36134205 http://dx.doi.org/10.2147/IJN.S377149 |