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Advances in Antitumor Nano-Drug Delivery Systems of 10-Hydroxycamptothecin

10-Hydroxycamptothecin (HCPT) is a natural plant alkaloid from Camptotheca that shows potent antitumor activity by targeting intracellular topoisomerase I. However, factors such as instability of the lactone ring and insolubility in water have limited the clinical application of this drug. In recent...

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Detalles Bibliográficos
Autores principales: Chen, Yukun, Wang, Zhenzhi, Wang, Xiaofan, Su, Mingliang, Xu, Fan, Yang, Lian, Jia, Lijun, Zhang, Zhanxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482956/
https://www.ncbi.nlm.nih.gov/pubmed/36134205
http://dx.doi.org/10.2147/IJN.S377149