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Immunotherapy in advanced kidney cancer: an alternative meta-analytic method using reconstructed survival data in case of proportional hazard assumption violation

BACKGROUND: With the advent of immuno-oncology compounds in randomized trials, we observe more and more survival curves crossing. From a statistical standpoint this corresponds to violation of the proportional hazard assumption. When this occurs, the hazard ratio from the Cox regression is not relia...

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Detalles Bibliográficos
Autores principales: Nocera, Luigi, Fallara, Giuseppe, Raggi, Daniele, Belladelli, Federico, Robesti, Daniele, Montorsi, Francesco, Karakiewicz, Pierre I., Malavaud, Bernard, Ploussard, Guillaume, Necchi, Andrea, Martini, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483094/
https://www.ncbi.nlm.nih.gov/pubmed/36132135
http://dx.doi.org/10.3389/fonc.2022.955894