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The cuproptosis-associated 13 gene signature as a robust predictor for outcome and response to immune- and targeted-therapies in clear cell renal cell carcinoma

Cuproptosis, the newly identified form of regulatory cell death (RCD), results from mitochondrial proteotoxic stress mediated by copper and FDX1. Little is known about significances of cuproptosis in oncogenesis. Here we determined clinical implications of cuproptosis in clear cell renal cell carcin...

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Detalles Bibliográficos
Autores principales: Yuan, Huiyang, Qin, Xin, Wang, Jing, Yang, Qingya, Fan, Yidong, Xu, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483097/
https://www.ncbi.nlm.nih.gov/pubmed/36131921
http://dx.doi.org/10.3389/fimmu.2022.971142