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α2-macroglobulin-rich serum as a master inhibitor of inflammatory factors attenuates cartilage degeneration in a mini pig model of osteoarthritis induced by “idealized” anterior cruciate ligament reconstruction

Post-traumatic osteoarthritis is a special type of osteoarthritis and a common disease, with few effective treatments available. α2-Macroglobulin (α2M) is important to chondral protection in post-traumatic osteoarthritis. However, its injection into xenogeneic joint cavities involves safety hazards,...

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Detalles Bibliográficos
Autores principales: Zhao, Ruipeng, Wei, Xiaochun, Zhang, Chengming, Wu, Hongru, Xiang, Chuan, Li, Haoqian, Duan, Wangping, Duan, Zhiqing, Li, Chunjiang, Zhao, Yu, Huang, Lingan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483147/
https://www.ncbi.nlm.nih.gov/pubmed/36133821
http://dx.doi.org/10.3389/fphar.2022.849102