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Anticancer effects of OSW-1 on glioma cells via regulation of the PI3K/AKT signal pathway: A network pharmacology approach and experimental validation in vitro and in vivo

Background: Gliomas are the most common primary intracranial malignant tumors with poor prognosis, despite the remarkable advances in medical technology that have been made. OSW-1, isolated from Ornithogalum saundersiae, possesses anticancer activity against various malignant cancer cells. However,...

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Detalles Bibliográficos
Autores principales: Zhan, Zhixin, Liu, Ziqiang, Zhang, Chaochao, Gao, Haijun, Lai, Jiacheng, Chen, Yong, Huang, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483153/
https://www.ncbi.nlm.nih.gov/pubmed/36133816
http://dx.doi.org/10.3389/fphar.2022.967141