Meprin β expression modulates the interleukin‐6 mediated JAK2‐STAT3 signaling pathway in ischemia/reperfusion‐induced kidney injury

Meprin metalloproteinases have been implicated in the pathophysiology of ischemia/reperfusion (IR)‐induced kidney injury. Previous in vitro data showed that meprin β proteolytically processes interleukin‐6 (IL‐6) resulting in its inactivation. Recently, meprin‐β was also shown to cleave the IL‐6 rec...

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Detalles Bibliográficos
Autores principales: Abousaad, Shaymaa, Ahmed, Faihaa, Abouzeid, Ayman, Ongeri, Elimelda Moige
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483619/
https://www.ncbi.nlm.nih.gov/pubmed/36117389
http://dx.doi.org/10.14814/phy2.15468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483619/
https://www.ncbi.nlm.nih.gov/pubmed/36117389
http://dx.doi.org/10.14814/phy2.15468

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