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Meprin β expression modulates the interleukin‐6 mediated JAK2‐STAT3 signaling pathway in ischemia/reperfusion‐induced kidney injury
Meprin metalloproteinases have been implicated in the pathophysiology of ischemia/reperfusion (IR)‐induced kidney injury. Previous in vitro data showed that meprin β proteolytically processes interleukin‐6 (IL‐6) resulting in its inactivation. Recently, meprin‐β was also shown to cleave the IL‐6 rec...
Autores principales: | Abousaad, Shaymaa, Ahmed, Faihaa, Abouzeid, Ayman, Ongeri, Elimelda Moige |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483619/ https://www.ncbi.nlm.nih.gov/pubmed/36117389 http://dx.doi.org/10.14814/phy2.15468 |
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