Protocol to downregulate GABAergic-astrocyte signaling via astrocyte-selective ablation of GABA(B) receptor in adult mice

Here, we present a protocol to selectively downregulate GABA(B) receptor (GABA(B)R) expression in astrocytes of mouse medial prefrontal cortex (mPFC). We first describe the procedure of surgeries and viral injections. We then detail genetic, histological, and functional characterizations of astrocyt...

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Detalles Bibliográficos
Autores principales: Mederos, Sara, Sánchez-Ruiz, Andrea, Perea, Gertrudis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483643/
https://www.ncbi.nlm.nih.gov/pubmed/36103305
http://dx.doi.org/10.1016/j.xpro.2022.101667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483643/
https://www.ncbi.nlm.nih.gov/pubmed/36103305
http://dx.doi.org/10.1016/j.xpro.2022.101667

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