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Protocol to downregulate GABAergic-astrocyte signaling via astrocyte-selective ablation of GABA(B) receptor in adult mice
Here, we present a protocol to selectively downregulate GABA(B) receptor (GABA(B)R) expression in astrocytes of mouse medial prefrontal cortex (mPFC). We first describe the procedure of surgeries and viral injections. We then detail genetic, histological, and functional characterizations of astrocyt...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483643/ https://www.ncbi.nlm.nih.gov/pubmed/36103305 http://dx.doi.org/10.1016/j.xpro.2022.101667 |