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Eomes function is conserved between zebrafish and mouse and controls left-right organiser progenitor gene expression via interlocking feedforward loops

The T-box family transcription factor Eomesodermin (Eomes) is present in all vertebrates, with many key roles in the developing mammalian embryo and immune system. Homozygous Eomes mutant mouse embryos exhibit early lethality due to defects in both the embryonic mesendoderm and the extraembryonic tr...

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Detalles Bibliográficos
Autores principales: Talbot, Conor D., Walsh, Mark D., Cutty, Stephen J., Elsayed, Randa, Vlachaki, Eirini, Bruce, Ashley E. E., Wardle, Fiona C., Nelson, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483813/
https://www.ncbi.nlm.nih.gov/pubmed/36133924
http://dx.doi.org/10.3389/fcell.2022.982477