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Eomes function is conserved between zebrafish and mouse and controls left-right organiser progenitor gene expression via interlocking feedforward loops
The T-box family transcription factor Eomesodermin (Eomes) is present in all vertebrates, with many key roles in the developing mammalian embryo and immune system. Homozygous Eomes mutant mouse embryos exhibit early lethality due to defects in both the embryonic mesendoderm and the extraembryonic tr...
Autores principales: | Talbot, Conor D., Walsh, Mark D., Cutty, Stephen J., Elsayed, Randa, Vlachaki, Eirini, Bruce, Ashley E. E., Wardle, Fiona C., Nelson, Andrew C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483813/ https://www.ncbi.nlm.nih.gov/pubmed/36133924 http://dx.doi.org/10.3389/fcell.2022.982477 |
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