Cargando…

Individual HLA heterogeneity and its implications for cellular immune evasion in cancer and beyond

Structural and functional variability of human leukocyte antigen (HLA) is the foundation for competent adaptive immune responses against pathogen and tumor antigens as it assures the breadth of the presented immune-peptidome, theoretically sustaining an efficient and diverse T cell response. This va...

Descripción completa

Detalles Bibliográficos
Autores principales: Pagliuca, Simona, Gurnari, Carmelo, Rubio, Marie Thérèse, Visconte, Valeria, Lenz, Tobias L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483928/
https://www.ncbi.nlm.nih.gov/pubmed/36131910
http://dx.doi.org/10.3389/fimmu.2022.944872