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Individual HLA heterogeneity and its implications for cellular immune evasion in cancer and beyond
Structural and functional variability of human leukocyte antigen (HLA) is the foundation for competent adaptive immune responses against pathogen and tumor antigens as it assures the breadth of the presented immune-peptidome, theoretically sustaining an efficient and diverse T cell response. This va...
Autores principales: | Pagliuca, Simona, Gurnari, Carmelo, Rubio, Marie Thérèse, Visconte, Valeria, Lenz, Tobias L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9483928/ https://www.ncbi.nlm.nih.gov/pubmed/36131910 http://dx.doi.org/10.3389/fimmu.2022.944872 |
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