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Structural topological analysis of spike proteins of SARS-CoV-2 variants of concern highlight distinctive amino acid substitution patterns

Since the onset of pandemic in 2019, SARS-CoV-2 has diverged into numerous variants driven by antigenic and infectivity-oriented selection. Some variants have accumulated fitness-enhancing mutations, evaded immunity and spread despite global vaccination campaigns. The spike (S) glycoprotein of SARS-...

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Detalles Bibliográficos
Autores principales: Peisahovics, Filips, Rohaim, Mohammed A., Munir, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier GmbH. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484102/
https://www.ncbi.nlm.nih.gov/pubmed/36156414
http://dx.doi.org/10.1016/j.ejcb.2022.151275