Combining a nanoparticle-mediated immunoradiotherapy with dual blockade of LAG3 and TIGIT improves the treatment efficacy in anti-PD1 resistant lung cancer

BACKGROUND: While improvements in immunoradiotherapy have significantly improved outcomes for cancer patients, this treatment approach has nevertheless proven ineffective at controlling the majority of malignancies. One of the mechanisms of resistance to immunoradiotherapy is that immune cells may b...

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Detalles Bibliográficos
Autores principales: Hu, Yun, Paris, Sébastien, Bertolet, Genevieve, Barsoumian, Hampartsoum B., He, Kewen, Sezen, Duygu, Chen, Dawei, Wasley, Mark, SILVA, Jordan DA, Mitchell, Joylise A., Voss, Tiffany A., Masrorpour, Fatemeh, Leyton, Claudia Kettlun, Yang, Liangpeng, Leuschner, Carola, Puebla-Osorio, Nahum, Gandhi, Saumil, Nguyen, Quynh-Nhu, Cortez, Maria Angelica, Welsh, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484155/
https://www.ncbi.nlm.nih.gov/pubmed/36123677
http://dx.doi.org/10.1186/s12951-022-01621-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484155/
https://www.ncbi.nlm.nih.gov/pubmed/36123677
http://dx.doi.org/10.1186/s12951-022-01621-4

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