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A robust and transformation-free joint model with matching and regularization for metagenomic trajectory and disease onset

BACKGROUND: To identify operational taxonomy units (OTUs) signaling disease onset in an observational study, a powerful strategy was selecting participants by matched sets and profiling temporal metagenomes, followed by trajectory analysis. Existing trajectory analyses modeled individual OTU or micr...

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Detalles Bibliográficos
Autores principales: Li, Qian, Vehik, Kendra, Li, Cai, Triplett, Eric, Roesch, Luiz, Hu, Yi-Juan, Krischer, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484160/
https://www.ncbi.nlm.nih.gov/pubmed/36123651
http://dx.doi.org/10.1186/s12864-022-08890-1