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A robust and transformation-free joint model with matching and regularization for metagenomic trajectory and disease onset
BACKGROUND: To identify operational taxonomy units (OTUs) signaling disease onset in an observational study, a powerful strategy was selecting participants by matched sets and profiling temporal metagenomes, followed by trajectory analysis. Existing trajectory analyses modeled individual OTU or micr...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484160/ https://www.ncbi.nlm.nih.gov/pubmed/36123651 http://dx.doi.org/10.1186/s12864-022-08890-1 |