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IRF7 expression correlates with HIV latency reversal upon specific blockade of immune activation

The persistence of latent HIV reservoirs allows for viral rebound upon antiretroviral therapy interruption, hindering effective HIV-1 cure. Emerging evidence suggests that modulation of innate immune stimulation could impact viral latency and contribute to the clearing of HIV reservoir. Here, the la...

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Detalles Bibliográficos
Autores principales: Ezeonwumelu, Ifeanyi Jude, García-Vidal, Edurne, Felip, Eudald, Puertas, Maria C., Oriol-Tordera, Bruna, Gutiérrez-Chamorro, Lucía, Gohr, André, Ruiz-Riol, Marta, Massanella, Marta, Clotet, Bonaventura, Martinez-Picado, Javier, Badia, Roger, Riveira-Muñoz, Eva, Ballana, Ester
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484258/
https://www.ncbi.nlm.nih.gov/pubmed/36131914
http://dx.doi.org/10.3389/fimmu.2022.1001068