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Specific transcriptional programs differentiate ICOS from CD28 costimulatory signaling in human Naïve CD4(+) T cells

Costimulatory molecules of the CD28 family play a crucial role in the activation of immune responses in T lymphocytes, complementing and modulating signals originating from the T-cell receptor (TCR) complex. Although distinct functional roles have been demonstrated for each family member, the specif...

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Detalles Bibliográficos
Autores principales: Gigliotti, Casimiro Luca, Boggio, Elena, Favero, Francesco, Incarnato, Danny, Santoro, Claudio, Oliviero, Salvatore, Rojo, Josè Maria, Zucchelli, Silvia, Persichetti, Francesca, Baldanzi, Gianluca, Dianzani, Umberto, Corà, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484324/
https://www.ncbi.nlm.nih.gov/pubmed/36131938
http://dx.doi.org/10.3389/fimmu.2022.915963