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Specific transcriptional programs differentiate ICOS from CD28 costimulatory signaling in human Naïve CD4(+) T cells
Costimulatory molecules of the CD28 family play a crucial role in the activation of immune responses in T lymphocytes, complementing and modulating signals originating from the T-cell receptor (TCR) complex. Although distinct functional roles have been demonstrated for each family member, the specif...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484324/ https://www.ncbi.nlm.nih.gov/pubmed/36131938 http://dx.doi.org/10.3389/fimmu.2022.915963 |