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Keratinocyte-derived S100A9 modulates neutrophil infiltration and affects psoriasis-like skin and joint disease

OBJECTIVES: S100A9, an alarmin that can form calprotectin (CP) heterodimers with S100A8, is mainly produced by keratinocytes and innate immune cells. The contribution of keratinocyte-derived S100A9 to psoriasis (Ps) and psoriatic arthritis (PsA) was evaluated using mouse models, and the potential us...

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Detalles Bibliográficos
Autores principales: Mellor, Liliana F, Gago-Lopez, Nuria, Bakiri, Latifa, Schmidt, Felix N, Busse, Björn, Rauber, Simon, Jimenez, Maria, Megías, Diego, Oterino-Sogo, Sergio, Sanchez-Prieto, Ricardo, Grivennikov, Sergei, Pu, Xinzhu, Oxford, Julia, Ramming, Andreas, Schett, Georg, Wagner, Erwin F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484400/
https://www.ncbi.nlm.nih.gov/pubmed/35788494
http://dx.doi.org/10.1136/annrheumdis-2022-222229