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Sophocarpine inhibits tumor progression by antagonizing the PI3K/AKT/mTOR signaling pathway in castration-resistant prostate cancer

OBJECTIVE: The objective of this study was to investigate the inhibitory effect of sophocarpine on the progression of castration-resistant prostate cancer (CRPC) and the underlying molecular mechanism. METHODS: DU145 and PC3 cells (two CRPC cell lines), incubated with different concentrations of sop...

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Detalles Bibliográficos
Autores principales: Weng, Min, Shi, Chenghao, Han, Hui, Zhu, Hengyue, Xiao, Yanyi, Guo, Hangcheng, Yu, Zhixian, Wu, Cunzao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484452/
https://www.ncbi.nlm.nih.gov/pubmed/36132221
http://dx.doi.org/10.7717/peerj.14042