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Sophocarpine inhibits tumor progression by antagonizing the PI3K/AKT/mTOR signaling pathway in castration-resistant prostate cancer
OBJECTIVE: The objective of this study was to investigate the inhibitory effect of sophocarpine on the progression of castration-resistant prostate cancer (CRPC) and the underlying molecular mechanism. METHODS: DU145 and PC3 cells (two CRPC cell lines), incubated with different concentrations of sop...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484452/ https://www.ncbi.nlm.nih.gov/pubmed/36132221 http://dx.doi.org/10.7717/peerj.14042 |