A polymorphic transcriptional regulatory domain in the amyotrophic lateral sclerosis risk gene CFAP410 correlates with differential isoform expression

We describe the characterisation of a variable number tandem repeat (VNTR) domain within intron 1 of the amyotrophic lateral sclerosis (ALS) risk gene CFAP410 (Cilia and flagella associated protein 410) (previously known as C21orf2), providing insight into how this domain could support differential...

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Detalles Bibliográficos
Autores principales: Marshall, Jack N. G., Fröhlich, Alexander, Li, Li, Pfaff, Abigail L., Middlehurst, Ben, Spargo, Thomas P., Iacoangeli, Alfredo, Lang, Bing, Al-Chalabi, Ammar, Koks, Sulev, Bubb, Vivien J., Quinn, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484465/
https://www.ncbi.nlm.nih.gov/pubmed/36131690
http://dx.doi.org/10.3389/fnmol.2022.954928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484465/
https://www.ncbi.nlm.nih.gov/pubmed/36131690
http://dx.doi.org/10.3389/fnmol.2022.954928

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