A Pragmatic, Data-Driven Method to Determine Cutoffs for CSF Biomarkers of Alzheimer Disease Based on Validation Against PET Imaging

BACKGROUND AND OBJECTIVES: To elaborate a new algorithm to establish a standardized method to define cutoffs for CSF biomarkers of Alzheimer disease (AD) by validating the algorithm against CSF classification derived from PET imaging. METHODS: Low and high levels of CSF phosphorylated tau were first...

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Detalles Bibliográficos
Autores principales: Dumurgier, Julien, Sabia, Séverine, Zetterberg, Henrik, Teunissen, Charlotte E., Hanseeuw, Bernard, Orellana, Adelina, Schraen, Susanna, Gabelle, Audrey, Boada, Mercè, Lebouvier, Thibaud, Willemse, Eline A.J., Cognat, Emmanuel, Ruiz, Agustin, Hourregue, Claire, Lilamand, Matthieu, Bouaziz-Amar, Elodie, Laplanche, Jean-Louis, Lehmann, Sylvain, Pasquier, Florence, Scheltens, Philip, Blennow, Kaj, Singh-Manoux, Archana, Paquet, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484605/
https://www.ncbi.nlm.nih.gov/pubmed/35970577
http://dx.doi.org/10.1212/WNL.0000000000200735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484605/
https://www.ncbi.nlm.nih.gov/pubmed/35970577
http://dx.doi.org/10.1212/WNL.0000000000200735

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