Identifying enhancer properties associated with genetic risk for complex traits using regulome-wide association studies

Genetic risk for complex traits is strongly enriched in non-coding genomic regions involved in gene regulation, especially enhancers. However, we lack adequate tools to connect the characteristics of these disruptions to genetic risk. Here, we propose RWAS (Regulome Wide Association Study), a new ap...

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Detalles Bibliográficos
Autores principales: Casella, Alex M., Colantuoni, Carlo, Ament, Seth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484640/
https://www.ncbi.nlm.nih.gov/pubmed/36070311
http://dx.doi.org/10.1371/journal.pcbi.1010430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484640/
https://www.ncbi.nlm.nih.gov/pubmed/36070311
http://dx.doi.org/10.1371/journal.pcbi.1010430

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