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Identifying enhancer properties associated with genetic risk for complex traits using regulome-wide association studies
Genetic risk for complex traits is strongly enriched in non-coding genomic regions involved in gene regulation, especially enhancers. However, we lack adequate tools to connect the characteristics of these disruptions to genetic risk. Here, we propose RWAS (Regulome Wide Association Study), a new ap...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484640/ https://www.ncbi.nlm.nih.gov/pubmed/36070311 http://dx.doi.org/10.1371/journal.pcbi.1010430 |