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Localized variation in ancestral admixture identifies pilocytic astrocytoma risk loci among Latino children

BACKGROUND: Pilocytic astrocytoma (PA) is the most common pediatric brain tumor. PA has at least a 50% higher incidence in populations of European ancestry compared to other ancestral groups, which may be due in part to genetic differences. METHODS: We first compared the global proportions of Europe...

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Detalles Bibliográficos
Autores principales: Li, Shaobo, Chiang, Charleston W. K., Myint, Swe Swe, Arroyo, Katti, Chan, Tsz Fung, Morimoto, Libby, Metayer, Catherine, de Smith, Adam J., Walsh, Kyle M., Wiemels, Joseph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484652/
https://www.ncbi.nlm.nih.gov/pubmed/36070312
http://dx.doi.org/10.1371/journal.pgen.1010388