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Low antithrombin levels are associated with low risk of cardiovascular death but are a risk factor for cancer mortality

BACKGROUND: Thrombosis is common in subjects suffering from cardiovascular diseases (CVD) and cancer. Hypercoagulation plays a pivotal role in the pathophysiology of thrombosis. Therefore, the inactivation of thrombin, the key enzyme in coagulation, is tightly regulated via antithrombin (AT). AT def...

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Detalles Bibliográficos
Autores principales: Iacoviello, Licia, de Laat-Kremers, Romy, Costanzo, Simona, Yan, Qiuting, Di Castelnuovo, Augusto, van der Vorm, Lisa, De Curtis, Amalia, Ninivaggi, Marisa, Cerletti, Chiara, Donati, Maria Benedetta, de Laat, Bas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484666/
https://www.ncbi.nlm.nih.gov/pubmed/36121817
http://dx.doi.org/10.1371/journal.pone.0271663