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Functional expression of diverse post-translational peptide-modifying enzymes in Escherichia coli under uniform expression and purification conditions

RiPPs (ribosomally-synthesized and post-translationally modified peptides) are a class of pharmaceutically-relevant natural products expressed as precursor peptides before being enzymatically processed into their final functional forms. Bioinformatic methods have illuminated hundreds of thousands of...

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Detalles Bibliográficos
Autores principales: Glassey, Emerson, King, Andrew M., Anderson, Daniel A., Zhang, Zhengan, Voigt, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484694/
https://www.ncbi.nlm.nih.gov/pubmed/36121811
http://dx.doi.org/10.1371/journal.pone.0266488