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Homologous recombination between tandem paralogues drives evolution of a subset of type VII secretion system immunity genes in firmicute bacteria

The type VII secretion system (T7SS) is found in many Gram-positive firmicutes and secretes protein toxins that mediate bacterial antagonism. Two T7SS toxins have been identified in Staphylococcus aureus , EsaD a nuclease toxin that is counteracted by the EsaG immunity protein, and TspA, which has m...

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Detalles Bibliográficos
Autores principales: Garrett, Stephen R., Mariano, Giuseppina, Dicks, Jo, Palmer, Tracy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484751/
https://www.ncbi.nlm.nih.gov/pubmed/35960642
http://dx.doi.org/10.1099/mgen.0.000868