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Punicalagin Attenuates LPS-Induced Inflammation and ROS Production in Microglia by Inhibiting the MAPK/NF-κB Signaling Pathway and NLRP3 Inflammasome Activation

PURPOSE: Neurodegenerative diseases are associated with neuroinflammation along with activation of microglia and oxidative stress, but currently lack effective treatments. Punicalagin is a natural bio-sourced product that exhibits anti-inflammatory effects on several chronic diseases; however, the a...

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Detalles Bibliográficos
Autores principales: Lo, Jung, Liu, Ching-Chih, Li, Yueh-Shan, Lee, Po-Yen, Liu, Po-Len, Wu, Pei-Chang, Lin, Tzu-Chieh, Chen, Chi-Shuo, Chiu, Chien-Chih, Lai, Yu-Hung, Chang, Yo-Chen, Wu, Hsin-En, Chen, Yuan-Ru, Huang, Yu-Kai, Huang, Shu-Pin, Wang, Shu-Chi, Li, Chia-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484772/
https://www.ncbi.nlm.nih.gov/pubmed/36131784
http://dx.doi.org/10.2147/JIR.S372773