Cargando…

Punicalagin Attenuates LPS-Induced Inflammation and ROS Production in Microglia by Inhibiting the MAPK/NF-κB Signaling Pathway and NLRP3 Inflammasome Activation

PURPOSE: Neurodegenerative diseases are associated with neuroinflammation along with activation of microglia and oxidative stress, but currently lack effective treatments. Punicalagin is a natural bio-sourced product that exhibits anti-inflammatory effects on several chronic diseases; however, the a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lo, Jung, Liu, Ching-Chih, Li, Yueh-Shan, Lee, Po-Yen, Liu, Po-Len, Wu, Pei-Chang, Lin, Tzu-Chieh, Chen, Chi-Shuo, Chiu, Chien-Chih, Lai, Yu-Hung, Chang, Yo-Chen, Wu, Hsin-En, Chen, Yuan-Ru, Huang, Yu-Kai, Huang, Shu-Pin, Wang, Shu-Chi, Li, Chia-Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484772/ https://www.ncbi.nlm.nih.gov/pubmed/36131784 http://dx.doi.org/10.2147/JIR.S372773

Ejemplares similares

Nordalbergin Exerts Anti-Neuroinflammatory Effects by Attenuating MAPK Signaling Pathway, NLRP3 Inflammasome Activation and ROS Production in LPS-Stimulated BV2 Microglia
por: Lo, Jung, et al.
Publicado: (2023)

Corylin inhibits LPS-induced inflammatory response and attenuates the activation of NLRP3 inflammasome in microglia
por: Huang, Ming-Yii, et al.
Publicado: (2018)

Zerumbone Suppresses the LPS-Induced Inflammatory Response and Represses Activation of the NLRP3 Inflammasome in Macrophages
por: Su, Chia-Cheng, et al.
Publicado: (2021)

Mycotoxin Zearalenone Attenuates Innate Immune Responses and Suppresses NLRP3 Inflammasome Activation in LPS-Activated Macrophages
por: Lee, Po-Yen, et al.
Publicado: (2021)

Protective Effect of Piplartine against LPS-Induced Sepsis through Attenuating the MAPKs/NF-κB Signaling Pathway and NLRP3 Inflammasome Activation
por: Huang, Chi-Han, et al.
Publicado: (2021)

The AST-120 Recovers Uremic Toxin-Induced Cognitive Deficit via NLRP3 Inflammasome Pathway in Astrocytes and Microglia
por: Li, Lung-Chih, et al.
Publicado: (2021)

Role of the NLRP3 Inflammasome: Insights Into Cancer Hallmarks
por: Lin, Ting-Yi, et al.
Publicado: (2021)

Activation of an NLRP3 Inflammasome Restricts Mycobacterium kansasii Infection
por: Chen, Chang-Chieh, et al.
Publicado: (2012)

A synthetic cationic antimicrobial peptide inhibits inflammatory response and the NLRP3 inflammasome by neutralizing LPS and ATP
por: Li, Lan-Hui, et al.
Publicado: (2017)

Loganin Attenuates High Glucose-Induced Schwann Cells Pyroptosis by Inhibiting ROS Generation and NLRP3 Inflammasome Activation
por: Cheng, Yu-Chi, et al.
Publicado: (2020)

GSDMD Mediates LPS-Induced Septic Myocardial Dysfunction by Regulating ROS-dependent NLRP3 Inflammasome Activation
por: Dai, Shanshan, et al.
Publicado: (2021)

Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock
por: Mao, Kairui, et al.
Publicado: (2013)

Dimethyl Fumarate Alleviates NLRP3 Inflammasome Activation in Microglia and Sickness Behavior in LPS-Challenged Mice
por: Tastan, Bora, et al.
Publicado: (2021)

NLRP12 Inflammasome Expression in the Rat Brain in Response to LPS during Morphine Tolerance
por: Chang, Sulie L., et al.
Publicado: (2017)

The natural tannins oligomeric proanthocyanidins and punicalagin are potent inhibitors of infection by SARS-CoV-2
por: Chen, Hsiao-Fan, et al.
Publicado: (2023)

BAFF-driven NLRP3 inflammasome activation in B cells
por: Lim, Ken-Hong, et al.
Publicado: (2020)

Ugonin U stimulates NLRP3 inflammasome activation and enhances inflammasome-mediated pathogen clearance
por: Chen, Chun-Yu, et al.
Publicado: (2016)

Corylin protects LPS-induced sepsis and attenuates LPS-induced inflammatory response
por: Hung, Yung-Li, et al.
Publicado: (2017)

Corticosterone Inhibits LPS-Induced NLRP3 Inflammasome Priming in Macrophages by Suppressing Xanthine Oxidase
por: Wu, Ling, et al.
Publicado: (2020)

Translational Medicine in Uremic Vascular Calcification: Scavenging ROS Attenuates p-Cresyl Sulfate-Activated Caspase-1, NLRP3 Inflammasome and Eicosanoid Inflammation in Human Arterial Smooth Muscle Cells
por: Chang, Jia-Feng, et al.
Publicado: (2022)

The Role of Microglia and the Nlrp3 Inflammasome in Alzheimer's Disease
por: Hanslik, Kendra L., et al.
Publicado: (2020)

Punicalagin Protects Diabetic Nephropathy by Inhibiting Pyroptosis Based on TXNIP/NLRP3 Pathway
por: An, Xin, et al.
Publicado: (2020)

TRPV1 channel mediates NLRP3 inflammasome-dependent neuroinflammation in microglia
por: Zhang, Yahui, et al.
Publicado: (2021)

Lung-protective effect of Punicalagin on LPS-induced acute lung injury in mice
por: Zeng, Yibin, et al.
Publicado: (2022)

Punicalin Ameliorates Cell Pyroptosis Induced by LPS/ATP Through Suppression of ROS/NLRP3 Pathway
por: Shen, Ruiting, et al.
Publicado: (2021)

SIRT1 Promotes M2 Microglia Polarization via Reducing ROS-Mediated NLRP3 Inflammasome Signaling After Subarachnoid Hemorrhage
por: Xia, Da-Yong, et al.
Publicado: (2021)

Punicalagin attenuates ventricular remodeling after acute myocardial infarction via regulating the NLRP3/caspase-1 pathway
por: Peng, Jian-fei, et al.
Publicado: (2023)

The Role of Interleukin-17A and NLRP3 Inflammasome in the Pathogenesis of Graves’ Ophthalmopathy
por: Lin, Chih-Chung, et al.
Publicado: (2023)

Glibenclamide Alleviates LPS-Induced Acute Lung Injury through NLRP3 Inflammasome Signaling Pathway
por: Yang, Jie, et al.
Publicado: (2022)

Oridonin Alleviates LPS-Induced Depression by Inhibiting NLRP3 Inflammasome via Activation of Autophagy
por: Li, Chunyan, et al.
Publicado: (2022)

SIRT1 Alleviates LPS-Induced IL-1β Production by Suppressing NLRP3 Inflammasome Activation and ROS Production in Trophoblasts
por: Park, Sumi, et al.
Publicado: (2020)

CVB3 Inhibits NLRP3 Inflammasome Activation by Suppressing NF-κB Pathway and ROS Production in LPS-Induced Macrophages
por: Wang, Yanqi, et al.
Publicado: (2023)

Discovery of 2-Substituted 3-Arylquinoline Derivatives as Potential Anti-Inflammatory Agents Through Inhibition of LPS-Induced Inflammatory Responses in Macrophages
por: Yang, Cheng-Yao, et al.
Publicado: (2019)

Corilagin Restrains NLRP3 Inflammasome Activation and Pyroptosis through the ROS/TXNIP/NLRP3 Pathway to Prevent Inflammation
por: Luo, Tianyu, et al.
Publicado: (2022)

The role of mitochondria-associated membranes mediated ROS on NLRP3 inflammasome in cardiovascular diseases
por: Zhao, Jiahao, et al.
Publicado: (2022)

NLRP3 Inflammasome Is Expressed and Functional in Mouse Brain Microglia but Not in Astrocytes
por: Gustin, Audrey, et al.
Publicado: (2015)

Microglia NLRP3 Inflammasome and Neuroimmune Signaling in Substance Use Disorders
por: Guo, Ming-Lei, et al.
Publicado: (2023)

Pretreatment of the ROS Inhibitor Phenyl-N-tert-butylnitrone Alleviates Sleep Deprivation-Induced Hyperalgesia by Suppressing Microglia Activation and NLRP3 Inflammasome Activity in the Spinal Dorsal Cord
por: Huang, Yulin, et al.
Publicado: (2022)

Coenzyme Q(0) Inhibits NLRP3 Inflammasome Activation through Mitophagy Induction in LPS/ATP-Stimulated Macrophages
por: Hseu, You-Cheng, et al.
Publicado: (2022)

Edaravone Plays Protective Effects on LPS-Induced Microglia by Switching M1/M2 Phenotypes and Regulating NLRP3 Inflammasome Activation
por: Li, Jiping, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_k9oniva3p73serpn43e0otlqir