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Proximal tubular epithelia-specific transcriptomics of diabetic mice treated with dapagliflozin
Based on recent clinical trials using sodium-glucose co-transporter 2 inhibitor (SGLT2i) demonstrating the significant improvement of outcomes of diabetic kidney disease (DKD), the paradigm shift from “glomerulocentric” to “tubule centric” pathophysiology in DKD progression has been highlighted. Sev...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485043/ https://www.ncbi.nlm.nih.gov/pubmed/36148274 http://dx.doi.org/10.1016/j.heliyon.2022.e10615 |