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Proximal tubular epithelia-specific transcriptomics of diabetic mice treated with dapagliflozin

Based on recent clinical trials using sodium-glucose co-transporter 2 inhibitor (SGLT2i) demonstrating the significant improvement of outcomes of diabetic kidney disease (DKD), the paradigm shift from “glomerulocentric” to “tubule centric” pathophysiology in DKD progression has been highlighted. Sev...

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Detalles Bibliográficos
Autores principales: Uehara-Watanabe, Noriko, Okuno-Ozeki, Natsuko, Nakamura, Itaru, Nakata, Tomohiro, Nakai, Kunihiro, Yagi-Tomita, Aya, Ida, Tomoharu, Yamashita, Noriyuki, Kamezaki, Michitsugu, Kirita, Yuhei, Matoba, Satoaki, Tamagaki, Keiichi, Kusaba, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485043/
https://www.ncbi.nlm.nih.gov/pubmed/36148274
http://dx.doi.org/10.1016/j.heliyon.2022.e10615