Glycosylation of a key cubilin Asn residue results in reduced binding to albumin

Kidney disease often manifests with an increase in proteinuria, which can result from both glomerular and/or proximal tubule injury. The proximal tubules are the major site of protein and peptide endocytosis of the glomerular filtrate, and cubilin is the proximal tubule brush border membrane glycopr...

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Detalles Bibliográficos
Autores principales: Yadav, Shiv Pratap Singh, Yu, Aiying, Zhao, Jingfu, Singh, Jasdeep, Kakkar, Saloni, Chakraborty, Srinivas, Mechref, Yehia, Molitoris, Bruce, Wagner, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485058/
https://www.ncbi.nlm.nih.gov/pubmed/35970386
http://dx.doi.org/10.1016/j.jbc.2022.102371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485058/
https://www.ncbi.nlm.nih.gov/pubmed/35970386
http://dx.doi.org/10.1016/j.jbc.2022.102371

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