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Inhibitors of RNA and protein synthesis cause Glut4 translocation and increase glucose uptake in adipocytes

Insulin stimulates glucose uptake in adipocytes by triggering translocation of glucose transporter 4-containg vesicles to the plasma membrane. Under basal conditions, these vesicles (IRVs for insulin-responsive vesicles) are retained inside the cell via a “static” or “dynamic” mechanism. We have fou...

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Detalles Bibliográficos
Autores principales: Meriin, A. B., Zaarur, N., Bogan, J. S., Kandror, K. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485115/
https://www.ncbi.nlm.nih.gov/pubmed/36123369
http://dx.doi.org/10.1038/s41598-022-19534-5