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Angiocrine extracellular vesicles impose mesenchymal reprogramming upon proneural glioma stem cells

Glioblastoma (GBM) is an incurable form of primary astrocytic brain tumor driven by glioma stem cell (GSC) compartment closely associated with the vascular niche. GSC phenotypes are heterogeneous and range from proneural to mesenchymal-like, the latter characterised by greater invasiveness. Here we...

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Detalles Bibliográficos
Autores principales: Adnani, Lata, Kassouf, Jordan, Meehan, Brian, Spinelli, Cristiana, Tawil, Nadim, Nakano, Ichiro, Rak, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485157/
https://www.ncbi.nlm.nih.gov/pubmed/36123372
http://dx.doi.org/10.1038/s41467-022-33235-7