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Angiocrine extracellular vesicles impose mesenchymal reprogramming upon proneural glioma stem cells
Glioblastoma (GBM) is an incurable form of primary astrocytic brain tumor driven by glioma stem cell (GSC) compartment closely associated with the vascular niche. GSC phenotypes are heterogeneous and range from proneural to mesenchymal-like, the latter characterised by greater invasiveness. Here we...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485157/ https://www.ncbi.nlm.nih.gov/pubmed/36123372 http://dx.doi.org/10.1038/s41467-022-33235-7 |