Cargando…

Angiocrine extracellular vesicles impose mesenchymal reprogramming upon proneural glioma stem cells

Glioblastoma (GBM) is an incurable form of primary astrocytic brain tumor driven by glioma stem cell (GSC) compartment closely associated with the vascular niche. GSC phenotypes are heterogeneous and range from proneural to mesenchymal-like, the latter characterised by greater invasiveness. Here we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Adnani, Lata, Kassouf, Jordan, Meehan, Brian, Spinelli, Cristiana, Tawil, Nadim, Nakano, Ichiro, Rak, Janusz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485157/ https://www.ncbi.nlm.nih.gov/pubmed/36123372 http://dx.doi.org/10.1038/s41467-022-33235-7

Ejemplares similares

Extracellular Vesicles as Conduits of Non-Coding RNA Emission and Intercellular Transfer in Brain Tumors
por: Spinelli, Cristiana, et al.
Publicado: (2018)

OPTC-5. Molecular signatures of podoplanin expressing glioblastoma cell subsets with putative role in cancer associated thrombosis and microthrombosis
por: Tawil, Nadim, et al.
Publicado: (2021)

Bone angiocrine factors
por: Ribatti, Domenico, et al.
Publicado: (2023)

Imposed Upon
Publicado: (1876)

Gene expression profiling distinguishes proneural glioma stem cells from mesenchymal glioma stem cells
por: Chandran, Uma R., et al.
Publicado: (2015)

Transcriptional Mechanisms of Proneural Factors and REST in Regulating Neuronal Reprogramming of Astrocytes
por: Masserdotti, Giacomo, et al.
Publicado: (2015)

Angiogenesis and angiocrines regulating heart growth
por: Hemanthakumar, Karthik Amudhala, et al.
Publicado: (2020)

Angiocrine endothelium: from physiology to cancer
por: Pasquier, Jennifer, et al.
Publicado: (2020)

Control of Tumor Progression by Angiocrine Factors
por: Alsina-Sanchis, Elisenda, et al.
Publicado: (2021)

Prominin 1/CD133 Endothelium Sustains Growth of Proneural Glioma
por: Ding, Bi-Sen, et al.
Publicado: (2013)

Extracellular vesicles from genetically unstable, oncogene-driven cancer cells trigger micronuclei formation in endothelial cells
por: Chennakrishnaiah, Shilpa, et al.
Publicado: (2020)

Endothelial-Myocardial Angiocrine Signaling in Heart Development
por: Kim, Hyeonyu, et al.
Publicado: (2021)

Notch Signaling Function in the Angiocrine Regulation of Tumor Development
por: Trindade, Alexandre, et al.
Publicado: (2020)

Role of angiocrine signals in bone development, homeostasis and disease
por: Sivan, Unnikrishnan, et al.
Publicado: (2019)

Tumor Angiocrine Signaling: Novel Targeting Opportunity in Cancer
por: Oria, Victor Oginga, et al.
Publicado: (2023)

Endothelial-derived angiocrine factors as instructors of embryonic development
por: Bishop, Daniel, et al.
Publicado: (2023)

Molecular subtypes and differentiation programmes of glioma stem cells as determinants of extracellular vesicle profiles and endothelial cell-stimulating activities
por: Spinelli, C., et al.
Publicado: (2018)

Quantitative proteomics and biological activity of extracellular vesicles engineered to express SARS‐CoV‐2 spike protein
por: Choi, Dongsic, et al.
Publicado: (2022)

The Proneural Molecular Signature Is Enriched in Oligodendrogliomas and Predicts Improved Survival among Diffuse Gliomas
por: Cooper, Lee A. D., et al.
Publicado: (2010)

Multi-site phospho-regulation of proneural transcription factors controls proliferation versus differentiation in development and reprogramming
por: Philpott, Anna
Publicado: (2015)

Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2
por: Kempf, J., et al.
Publicado: (2021)

Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2
por: Kempf, J., et al.
Publicado: (2021)

CDK4/6 inhibition is more active against the glioblastoma proneural subtype
por: Li, Ming, et al.
Publicado: (2017)

Angiocrine signals regulate quiescence and therapy resistance in bone metastasis
por: Singh, Amit, et al.
Publicado: (2019)

Angiocrine Regulation of Epithelial Barrier Integrity in Inflammatory Bowel Disease
por: Stürzl, Michael, et al.
Publicado: (2021)

Proneural and mesenchymal glioma stem cells display major differences in splicing and lncRNA profiles
por: Guardia, Gabriela D. A., et al.
Publicado: (2020)

Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration
por: Ding, Bi-Sen, et al.
Publicado: (2010)

Angiocrine Wnt signaling controls liver growth and metabolic maturation in mice
por: Leibing, Thomas, et al.
Publicado: (2018)

Suppression of CCL2 angiocrine function by adrenomedullin promotes tumor growth
por: Nakayama, Akiko, et al.
Publicado: (2022)

Oncostatin-M Differentially Regulates Mesenchymal and Proneural Signature Genes in Gliomas via STAT3 Signaling()
por: Natesh, Kumar, et al.
Publicado: (2015)

Phospholipase C Beta 1: a Candidate Signature Gene for Proneural Subtype High-Grade Glioma
por: Lu, Guangrong, et al.
Publicado: (2015)

American Quackery: How the Sick Are Imposed Upon—Ingenious Swindlers!
Publicado: (1869)

LonP1 Drives Proneural Mesenchymal Transition in IDH1-R132H Diffuse Glioma
por: Douglas, Christopher, et al.
Publicado: (2023)

Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis
por: Ding, Bi-Sen, et al.
Publicado: (2013)

Platelets prime hematopoietic–vascular niche to drive angiocrine-mediated liver regeneration
por: Shido, Koji, et al.
Publicado: (2017)

Endothelial Jak3 expression enhances pro-hematopoietic angiocrine function in mice
por: Barcia Durán, José Gabriel, et al.
Publicado: (2021)

Exonic splicing signals impose constraints upon the evolution of enzymatic activity
por: Falanga, Alessia, et al.
Publicado: (2014)

miR-34a Repression in Proneural Malignant Gliomas Upregulates Expression of Its Target PDGFRA and Promotes Tumorigenesis
por: Silber, Joachim, et al.
Publicado: (2012)

The clinical value of proneural, classical and mesenchymal protein signatures in WHO 2021 adult-type diffuse lower-grade gliomas
por: Dénes, Anna, et al.
Publicado: (2023)

Concerted regulation of retinal pigment epithelium basement membrane and barrier function by angiocrine factors
por: Benedicto, Ignacio, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_s006rlsh25paegv30kr5t6ee3j