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A stem cell roadmap of ribosome heterogeneity reveals a function for RPL10A in mesoderm production

Recent findings suggest that the ribosome itself modulates gene expression. However, whether ribosomes change composition across cell types or control cell fate remains unknown. Here, employing quantitative mass spectrometry during human embryonic stem cell differentiation, we identify dozens of rib...

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Detalles Bibliográficos
Autores principales: Genuth, Naomi R., Shi, Zhen, Kunimoto, Koshi, Hung, Victoria, Xu, Adele F., Kerr, Craig H., Tiu, Gerald C., Oses-Prieto, Juan A., Salomon-Shulman, Rachel E. A., Axelrod, Jeffrey D., Burlingame, Alma L., Loh, Kyle M., Barna, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485161/
https://www.ncbi.nlm.nih.gov/pubmed/36123354
http://dx.doi.org/10.1038/s41467-022-33263-3