Cargando…

A stem cell roadmap of ribosome heterogeneity reveals a function for RPL10A in mesoderm production

Recent findings suggest that the ribosome itself modulates gene expression. However, whether ribosomes change composition across cell types or control cell fate remains unknown. Here, employing quantitative mass spectrometry during human embryonic stem cell differentiation, we identify dozens of rib...

Descripción completa

Detalles Bibliográficos
Autores principales:	Genuth, Naomi R., Shi, Zhen, Kunimoto, Koshi, Hung, Victoria, Xu, Adele F., Kerr, Craig H., Tiu, Gerald C., Oses-Prieto, Juan A., Salomon-Shulman, Rachel E. A., Axelrod, Jeffrey D., Burlingame, Alma L., Loh, Kyle M., Barna, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485161/ https://www.ncbi.nlm.nih.gov/pubmed/36123354 http://dx.doi.org/10.1038/s41467-022-33263-3

Ejemplares similares

Evidence of Horizontal Gene Transfer of 50S Ribosomal Genes rplB, rplD, and rplY in Neisseria gonorrhoeae
por: Manoharan-Basil, Sheeba Santhini, et al.
Publicado: (2021)

The Ribosomal Protein Rpl22 Controls Ribosome Composition by Directly Repressing Expression of Its Own Paralog, Rpl22l1
por: O'Leary, Monique N., et al.
Publicado: (2013)

Eukaryotic rpL10 drives ribosomal rotation
por: Sulima, Sergey O., et al.
Publicado: (2014)

Functional analysis of Saccharomyces cerevisiae ribosomal protein Rpl3p in ribosome synthesis
por: Rosado, Iván V., et al.
Publicado: (2007)

Dynamic interplay between RPL3- and RPL3L-containing ribosomes modulates mitochondrial activity in the mammalian heart
por: Milenkovic, Ivan, et al.
Publicado: (2023)

Plant Ribosomal Proteins, RPL12 and RPL19, Play a Role in Nonhost Disease Resistance against Bacterial Pathogens
por: Nagaraj, Satish, et al.
Publicado: (2016)

RPL-4 and RPL-9 –Mediated Ribosome Purifications Facilitate the Efficient Analysis of Gene Expression in Caenorhabditis elegans Germ Cells
por: Nousch, Marco
Publicado: (2020)

Paralog-Specific Functions of RPL7A and RPL7B Mediated by Ribosomal Protein or snoRNA Dosage in Saccharomyces cerevisiae
por: Palumbo, Ryan J., et al.
Publicado: (2016)

Ribosomal protein gene RPL9 variants can differentially impair ribosome function and cellular metabolism
por: Lezzerini, Marco, et al.
Publicado: (2020)

Methylation of yeast ribosomal protein Rpl3 promotes translational elongation fidelity
por: Al-Hadid, Qais, et al.
Publicado: (2016)

Dosage Sensitivity of RPL9 and Concerted Evolution of Ribosomal Protein Genes in Plants
por: Devis, Deborah, et al.
Publicado: (2015)

TMEM16K is an interorganelle regulator of endosomal sorting
por: Petkovic, Maja, et al.
Publicado: (2020)

Distinct overlapping functions for Prickle1 and Prickle2 in the polarization of the airway epithelium
por: Kunimoto, Koshi, et al.
Publicado: (2022)

Molecular Characterization of AMPA-Receptor-Containing Vesicles
por: Peters, John Jacob, et al.
Publicado: (2021)

Eukaryotic Cells Producing Ribosomes Deficient in Rpl1 Are Hypersensitive to Defects in the Ubiquitin-Proteasome System
por: McIntosh, Kerri B., et al.
Publicado: (2011)

Identifying Neisseria Species by Use of the 50S Ribosomal Protein L6 (rplF) Gene
por: Bennett, Julia S., et al.
Publicado: (2014)

Structure of the JmjC domain-containing protein NO66 complexed with ribosomal protein Rpl8
por: Wang, Chengliang, et al.
Publicado: (2015)

The ribosomal protein gene RPL5 is a haploinsufficient tumor suppressor in multiple cancer types
por: Fancello, Laura, et al.
Publicado: (2017)

Puf6 and Loc1 Are the Dedicated Chaperones of Ribosomal Protein Rpl43 in Saccharomyces cerevisiae
por: Liang, Kai-Jen, et al.
Publicado: (2019)

Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis
por: Zou, Qianxing, et al.
Publicado: (2021)

Ribosomal protein L31 (RPL31) inhibits the proliferation and migration of gastric cancer cells
por: Wu, Fang, et al.
Publicado: (2023)

RPL3L-containing ribosomes determine translation elongation dynamics required for cardiac function
por: Shiraishi, Chisa, et al.
Publicado: (2023)

Ribosomal protein RPL11 haploinsufficiency causes anemia in mice via activation of the RP-MDM2-p53 pathway
por: Franklin, Derek A., et al.
Publicado: (2022)

Endogenous ribosomal protein L29 (RPL29): a newly identified regulator of angiogenesis in mice
por: Jones, Dylan T., et al.
Publicado: (2013)

The T-cell leukemia associated ribosomal RPL10 R98S mutation enhances JAK-STAT signaling
por: Girardi, Tiziana, et al.
Publicado: (2017)

The ribosomal RPL10 R98S mutation drives IRES-dependent BCL-2 translation in T-ALL
por: Kampen, Kim R., et al.
Publicado: (2018)

The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35
por: Liu, Pei Y., et al.
Publicado: (2019)

Silencing of Ribosomal Protein L34 (RPL34) Inhibits the Proliferation and Invasion of Esophageal Cancer Cells
por: Fan, Huijie, et al.
Publicado: (2017)

RPL26/uL24 UFMylation is essential for ribosome-associated quality control at the endoplasmic reticulum
por: Scavone, Francesco, et al.
Publicado: (2023)

RPL26/uL24 UFMylation is essential for ribosome-associated quality control at the endoplasmic reticulum
por: Scavone, Francesco, et al.
Publicado: (2023)

Capture, Release, and Identification of Newly Synthesized Proteins for Improved Profiling of Functional Translatomes
por: Phillips, Nancy J., et al.
Publicado: (2023)

Reduced expression of the mouse ribosomal protein Rpl17 alters the diversity of mature ribosomes by enhancing production of shortened 5.8S rRNA
por: Wang, Minshi, et al.
Publicado: (2015)

Composition and origin of lung fluid proteome in premature infants and relationship to respiratory outcome
por: Ballard, Philip L., et al.
Publicado: (2020)

Comparative Proteomics of Coxiella like Endosymbionts (CLEs) in the Symbiotic Organs of Rhipicephalus sanguineus Ticks
por: Cibichakravarthy, Balasubramanian, et al.
Publicado: (2022)

Non-specific recognition of histone modifications by H3K9bhb antibody
por: Tsusaka, Takeshi, et al.
Publicado: (2023)

An ancient spliceosomal intron in the ribosomal protein L7a gene (Rpl7a) of Giardia lamblia
por: Russell, Anthony G, et al.
Publicado: (2005)

siRNA Knockdown of Ribosomal Protein Gene RPL19 Abrogates the Aggressive Phenotype of Human Prostate Cancer
por: Bee, Alix, et al.
Publicado: (2011)

p73 expression is regulated by ribosomal protein RPL26 through mRNA translation and protein stability
por: Zhang, Min, et al.
Publicado: (2016)

Ribosomal Protein RPL10A Contributes to Early Plant Development and Abscisic Acid-Dependent Responses in Arabidopsis
por: Ramos, Rocío Soledad, et al.
Publicado: (2020)

Correction: The ribosomal RPL10 R98S mutation drives IRES-dependent BCL-2 translation in T-ALL
por: Kampen, Kim R., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ibcbaskpi4gcojn3rcgsop2e44