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H3K27m3 overexpression as a new, BCL2 independent diagnostic tool in follicular and cutaneous follicle center lymphomas

Approximately 15% of follicular lymphomas (FL) lack overexpression of BCL2 and the underlying translocation t(14;18). These cases can be diagnostically challenging, especially regarding follicular hyperplasia (FH). In a subset of FL, mutations in genes encoding for epigenetic modifiers, such as the...

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Detalles Bibliográficos
Autores principales: Brune, Magdalena M., Vela, Visar, Bratic Hench, Ivana, Dertinger, Susanne, Borgmann, Vanessa, Dirnhofer, Stefan, Tzankov, Alexandar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485181/
https://www.ncbi.nlm.nih.gov/pubmed/35661922
http://dx.doi.org/10.1007/s00428-022-03347-y