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The ERK5/NF-κB signaling pathway targets endometrial cancer proliferation and survival

Endometrial cancer (EC) is the most common type of gynecologic cancer in women of developed countries. Despite surgery combined with chemo-/radiotherapy regimens, overall survival of patients with high-risk EC tumors is poor, indicating a need for novel therapies. The MEK5-ERK5 pathway is activated...

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Detalles Bibliográficos
Autores principales: Diéguez-Martínez, Nora, Espinosa-Gil, Sergio, Yoldi, Guillermo, Megías-Roda, Elisabet, Bolinaga-Ayala, Idoia, Viñas-Casas, Maria, Gorgisen, Gokhan, Domingo-Ortí, Inés, Pérez-Montoyo, Héctor, Bayascas, Jose R., Colas, Eva, Dolcet, Xavier, Lizcano, Jose M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485191/
https://www.ncbi.nlm.nih.gov/pubmed/36123565
http://dx.doi.org/10.1007/s00018-022-04541-6