Tetratricopeptide repeat domain 36 deficiency mitigates renal tubular injury by inhibiting TGF-β1-induced epithelial–mesenchymal transition in a mouse model of chronic kidney disease

The damage of proximal tubular epithelial cells (PTECs) is considered a central event in the pathogenesis of chronic kidney disease (CKD) and deregulated repair processes of PTECs result in epithelial–mesenchymal transition (EMT), which in turn aggravates tubular injury and kidney fibrosis. In this...

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Detalles Bibliográficos
Autores principales: Yan, Xin, Peng, Rui, Ni, Yilu, Chen, Lei, He, Qingling, Li, Qianyin, Zhou, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2021
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485203/
https://www.ncbi.nlm.nih.gov/pubmed/36157495
http://dx.doi.org/10.1016/j.gendis.2021.04.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485203/
https://www.ncbi.nlm.nih.gov/pubmed/36157495
http://dx.doi.org/10.1016/j.gendis.2021.04.005

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