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PGRN exacerbates the progression of non-small cell lung cancer via PI3K/AKT/Bcl-2 antiapoptotic signaling

Progranulin (PGRN) is a growth factor that is involved in the progression of multiple tumors. However, the effects and molecular mechanisms by which PGRN induces lung cancer remain unclear. The expression level of PGRN was analyzed by conducting immunohistochemistry of the histological sections of l...

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Detalles Bibliográficos
Autores principales: Chen, Sicheng, Bie, Mengjun, Wang, Xiaowen, Fan, Mengtian, Chen, Bin, Shi, Qiong, Jiang, Yingjiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485207/
https://www.ncbi.nlm.nih.gov/pubmed/36157487
http://dx.doi.org/10.1016/j.gendis.2021.05.005