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Differences in integration frequencies and APOBEC3 profiles of five high-risk HPV types adheres to phylogeny

Persistent infection with Human Papillomavirus (HPV) is responsible for almost all cases of cervical cancers, and HPV16 and HPV18 associated with the majority of these. These types differ in the proportion of viral minor nucleotide variants (MNVs) caused by APOBEC3 mutagenesis as well as integration...

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Detalles Bibliográficos
Autores principales: Løvestad, Alexander Hesselberg, Repesa, Adina, Costanzi, Jean-Marc, Lagström, Sonja, Christiansen, Irene Kraus, Rounge, Trine B., Ambur, Ole Herman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485212/
https://www.ncbi.nlm.nih.gov/pubmed/36100161
http://dx.doi.org/10.1016/j.tvr.2022.200247