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Functional high-throughput screen identifies microRNAs that promote butyrate-induced death in colorectal cancer cells

The gut fermentation product butyrate displays anti-cancer properties in the human proximal colon, including the ability to inhibit proliferation and induce apoptosis in colorectal cancer (CRC) cells. A natural histone deacetylase inhibitor (HDACi), butyrate can alter histone acetylation patterns in...

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Detalles Bibliográficos
Autores principales: Ali, Saira R., Humphreys, Karen J., Simpson, Kaylene.J., McKinnon, Ross A., Meech, Robyn, Michael, Michael Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485215/
https://www.ncbi.nlm.nih.gov/pubmed/36189423
http://dx.doi.org/10.1016/j.omtn.2022.08.037