The therapeutic effect of KSP inhibitors in preclinical models of cholangiocarcinoma

Cholangiocarcinoma (CCA) is an epithelial malignancy with a dismal prognosis owing to limited treatment options. Here, we identified several compound candidates against CCA using a high-throughput drug screen with approved or emerging oncology drugs, among which kinesin spindle protein (KSP) inhibit...

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Detalles Bibliográficos
Autores principales: Shi, Yuanyuan, Cui, Xiaowen, Jiang, Tianyi, Pan, Yufei, Lin, Yunkai, Feng, Xiaofan, Ding, Zhiwen, Yang, Chun, Tan, Yexiong, Wang, Hongyang, Dong, Liwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485230/
https://www.ncbi.nlm.nih.gov/pubmed/36123339
http://dx.doi.org/10.1038/s41419-022-05247-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485230/
https://www.ncbi.nlm.nih.gov/pubmed/36123339
http://dx.doi.org/10.1038/s41419-022-05247-0

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