Stress induced TDP-43 mobility loss independent of stress granules

TAR DNA binding protein 43 (TDP-43) is closely related to the pathogenesis of amyotrophic lateral sclerosis (ALS) and translocates to stress granules (SGs). The role of SGs as aggregation-promoting “crucibles” for TDP-43, however, is still under debate. We analyzed TDP-43 mobility and localization u...

Descripción completa

Detalles Bibliográficos
Autores principales: Streit, Lisa, Kuhn, Timo, Vomhof, Thomas, Bopp, Verena, Ludolph, Albert C., Weishaupt, Jochen H., Gebhardt, J. Christof M., Michaelis, Jens, Danzer, Karin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485239/
https://www.ncbi.nlm.nih.gov/pubmed/36123343
http://dx.doi.org/10.1038/s41467-022-32939-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9485239/
https://www.ncbi.nlm.nih.gov/pubmed/36123343
http://dx.doi.org/10.1038/s41467-022-32939-0

Ejemplares similares